HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Arnon Nagler Selected Research

halofuginone

6/2015Halofuginone inhibits phosphorylation of SMAD-2 reducing angiogenesis and leukemia burden in an acute promyelocytic leukemia mouse model.
11/2012Inhibition of matrix metalloproteinase-2 by halofuginone is mediated by the Egr1 transcription factor.
6/2012Halofuginone inhibits multiple myeloma growth in vitro and in vivo and enhances cytotoxicity of conventional and novel agents.
1/2012Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice.
1/2011Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway.
10/2010Inhibition of pancreatic stellate cell activation by halofuginone prevents pancreatic xenograft tumor development.
5/2009Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention.
11/2008Prevention of muscle fibrosis and improvement in muscle performance in the mdx mouse by halofuginone.
9/2008Myofibroblasts in pulmonary and brain metastases of alveolar soft-part sarcoma: a novel target for treatment?
2/2007Inhibition of fibroblast to myofibroblast transition by halofuginone contributes to the chemotherapy-mediated antitumoral effect.
For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Arnon Nagler Research Topics

Disease

189Leukemia
10/2022 - 01/2002
154Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2022 - 01/2002
94Neoplasms (Cancer)
01/2022 - 01/2002
82Graft vs Host Disease (Graft-Versus-Host Disease)
10/2022 - 12/2002
59Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
03/2022 - 01/2002
54Multiple Myeloma
01/2022 - 12/2002
32Hematologic Neoplasms (Hematological Malignancy)
01/2022 - 03/2002
24BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2022 - 01/2002
24Lymphoma (Lymphomas)
12/2021 - 08/2003
21Infections
12/2021 - 12/2002
17Myelodysplastic Syndromes (Myelodysplastic Syndrome)
11/2021 - 12/2007
17Bronchiolitis Obliterans Syndrome
11/2021 - 08/2002
14Pathologic Complete Response
10/2022 - 10/2004
13B-Cell Lymphoma (Lymphoma, B Cell)
01/2022 - 11/2007
12Non-Hodgkin Lymphoma (Lymphosarcoma)
11/2021 - 01/2002
10Neoplasm Metastasis (Metastasis)
10/2018 - 12/2002
9Philadelphia Chromosome
01/2021 - 04/2006
9Fibrosis (Cirrhosis)
01/2013 - 07/2003
8Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2021 - 01/2008
8Residual Neoplasm
12/2020 - 01/2004
8Chromosome Aberrations (Chromosome Abnormalities)
01/2020 - 10/2007
7Primary Myelofibrosis (Myelosclerosis)
11/2021 - 12/2009
7Inflammation (Inflammations)
01/2021 - 08/2009
7Melanoma (Melanoma, Malignant)
01/2020 - 03/2006
7Hodgkin Disease (Hodgkin's Disease)
11/2018 - 06/2003
7Disease Progression
06/2015 - 03/2007
6Hematologic Diseases (Blood Diseases)
01/2021 - 01/2013
6Blast Crisis (Blast Phase)
10/2019 - 01/2002
6Neutropenia
10/2019 - 08/2003
5Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
01/2019 - 01/2012
5Thrombocytopenia (Thrombopenia)
01/2018 - 06/2010
4B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
02/2019 - 01/2002
3Polycythemia Vera
12/2022 - 12/2009

Drug/Important Bio-Agent (IBA)

49Cyclophosphamide (Cytoxan)FDA LinkGeneric
10/2022 - 10/2013
28fludarabineIBA
01/2022 - 12/2002
27Busulfan (Busulfex)FDA Link
01/2022 - 01/2003
24Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA
01/2022 - 12/2002
19halofuginoneIBA
06/2015 - 05/2002
16Chimeric Antigen ReceptorsIBA
01/2022 - 09/2014
13Bortezomib (Velcade)FDA Link
12/2020 - 04/2006
11Melphalan (Alkeran)FDA LinkGeneric
01/2022 - 12/2002
11Tyrosine Kinase InhibitorsIBA
01/2022 - 06/2010
11Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric
01/2022 - 01/2016
11heparanaseIBA
12/2021 - 01/2002
11Granulocyte Colony-Stimulating Factor (G-CSF)IBA
12/2021 - 01/2004
11Proteins (Proteins, Gene)FDA Link
02/2017 - 01/2002
11Imatinib Mesylate (Gleevec)FDA Link
05/2014 - 10/2004
10treosulfanIBA
01/2022 - 12/2007
10AntibodiesIBA
01/2020 - 05/2002
10CollagenIBA
11/2012 - 05/2002
9Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2022 - 01/2003
9Pharmaceutical PreparationsIBA
12/2019 - 09/2003
9LigandsIBA
01/2019 - 06/2005
8Methotrexate (Mexate)FDA LinkGeneric
01/2022 - 01/2003
8AntigensIBA
01/2022 - 03/2003
7HLA Antigens (Human Leukocyte Antigens)IBA
01/2022 - 11/2008
6Mycophenolic Acid (Cellcept)FDA LinkGeneric
01/2022 - 03/2016
6Rituximab (Mabthera)FDA Link
01/2018 - 08/2003
6Azacitidine (5 Azacytidine)FDA Link
04/2017 - 05/2010
6Collagen Type I (Type I Collagen)IBA
02/2007 - 07/2003
5Lenalidomide (CC 5013)FDA Link
01/2021 - 04/2008
5SteroidsIBA
02/2020 - 12/2002
5GlobulinsIBA
02/2020 - 01/2003
5tisagenlecleucelIBA
01/2020 - 01/2019
5Monoclonal AntibodiesIBA
01/2019 - 01/2003
51-dodecylpyridoxal (PLD)IBA
07/2016 - 09/2007
5liposomal doxorubicin (Doxil)FDA Link
07/2016 - 09/2007
5BKT140IBA
05/2014 - 03/2011
4Calcineurin InhibitorsIBA
01/2021 - 03/2016
4Dexamethasone (Maxidex)FDA LinkGeneric
12/2020 - 01/2012
4Thomsen-Friedenreich antibodiesIBA
02/2020 - 01/2003
4Sorafenib (BAY 43-9006)FDA Link
03/2019 - 01/2018
4RNA (Ribonucleic Acid)IBA
01/2019 - 01/2002
4EnzymesIBA
10/2018 - 09/2008
4Interleukin-15 (Interleukin 15)IBA
04/2018 - 08/2003
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
06/2015 - 09/2004
4AlkaloidsIBA
06/2015 - 01/2011
4CytokinesIBA
12/2014 - 04/2010
4Thalidomide (Thalomid)FDA Link
09/2014 - 11/2004
4Interleukin-2 (IL2)IBA
09/2013 - 05/2009
4Transforming Growth Factor beta (TGF-beta)IBA
01/2011 - 09/2008
4Interleukin-12 (IL 12)IBA
09/2004 - 03/2003
3Alemtuzumab (Campath)FDA Link
01/2022 - 06/2005

Therapy/Procedure

185Transplantation
10/2022 - 08/2002
155Stem Cell Transplantation
10/2022 - 01/2002
90Therapeutics
12/2022 - 03/2002
82Hematopoietic Stem Cell Transplantation
10/2022 - 01/2002
61Cell Transplantation
10/2022 - 02/2013
45Drug Therapy (Chemotherapy)
03/2022 - 01/2002
24Immunotherapy
01/2020 - 01/2002
22Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2022 - 08/2002
20Haploidentical Transplantation
01/2022 - 04/2015
17Homologous Transplantation
01/2020 - 01/2002
8Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
10/2022 - 04/2004
5Autologous Transplantation
01/2022 - 01/2010
5Salvage Therapy
01/2020 - 03/2008
5Cell- and Tissue-Based Therapy (Cell Therapy)
01/2013 - 03/2006
4Hematopoietic Stem Cell Mobilization
09/2021 - 01/2014
4Radiotherapy
01/2018 - 05/2005
3Induction Chemotherapy
02/2022 - 01/2021